Which of the followings are true about Vmax? A. The higher the [enzyme], the higher the Vmax B. Vmax is proportional to k2 C. Vmax is proportional to km D. Vmax is proportional to k1

Correct answer is A.

The higher the enzyme, the higher the Vmax

Explanation:

Although, in the absence of enzyme, the rate of a reaction (Vmax) increase linearly with substrate concentration. The reaction rate is given as dp/dt.

The rate of a reaction involving enzyme also increases.

At low enzyme concentrations or high substrate concentrations, all of the available enzyme active sites could be occupied with substrates. Therefore, increasing the substrate concentration further will not change the rate of diffusion. In other words, there is some maximum reaction rate (Vmax) when all enzyme active sites are occupied. The reaction rate will increase with increasing substrate concentration, but must asymptotically approach the saturation rate, Vmax. Vmax is directly proportional to the total enzyme concentration, E